METABOLOMIC SIGNATURES OF AGE, EXTREME OLD AGE, AND LONGEVITY IN LONG LIFE FAMILY STUDY PARTICIPANTS
Paola Sebastiani, Zeyuan Sog, Michael Lustgarten, Thomas Perls, Stefano Monti, Stacy Andersen, Michaela Schwaiger-Haber, Gary Patti · 2023
Read METABOLOMIC SIGNATURES OF AGE, EXTREME OLD AGE, AND LONGEVITY IN LONG LIFE FAMILY STUDY PARTICIPANTS by Paola Sebastiani, Zeyuan Sog, Michael Lustgarten, Thomas Perls, Stefano Monti, Stacy Andersen, Michaela Schwaiger-Haber, Gary Patti (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10737455.txt.
Description
Sebastiani and seven co-authors profiled blood chemistry across the lifespan in this study from twenty twenty-three. The samples came from the Long Life Family Study, whose members range from thirty to one hundred ten years old. About two thousand seven hundred people had over four hundred metabolites and fats measured. Family links and genome data were folded into the models.
Three hundred five compounds tracked age itself, including known markers that fell as years rose. Thirty more set centenarians apart from merely old participants. One hundred forty-four compounds predicted who would survive the follow-up years. The aging signature leaned on sugars, organic acids, and several fat classes. The authors note wide person-to-person spread at every age.
Catalog record
| CREATOR | Paola Sebastiani, Zeyuan Sog, Michael Lustgarten, Thomas Perls, Stefano Monti, Stacy Andersen, Michaela Schwaiger-Haber, Gary Patti |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |