ASSOCIATIONS OF ACTIGRAPHIC SLEEP WITH ADIPOKINES IN OLDER ADULTS
Yiwei Yue, Zhikui Wei, Jill Rabinowitz, Chee Chia, Toshiko Tanaka, Eleanor Simonsick, Luigi Ferrucci, Adam Spira · 2023
Read ASSOCIATIONS OF ACTIGRAPHIC SLEEP WITH ADIPOKINES IN OLDER ADULTS by Yiwei Yue, Zhikui Wei, Jill Rabinowitz, Chee Chia, Toshiko Tanaka, Eleanor Simonsick, Luigi Ferrucci, Adam Spira (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10737377.txt.
Description
Yiwei Yue and co-authors tie fragmented sleep to the hormone-like signals fat tissue sends the body. In three hundred fifty-three older adults from the Baltimore Longitudinal Study of Aging, wrist actigraphy recorded about a week of sleep. Fasting blood then measured two adipokines, adiponectin and leptin, that govern metabolism.
The key measure was average wake bout length, how long each nighttime waking lasts. Longer bouts meant lower levels of both adipokines, after adjusting for demographics, body mass, blood pressure, and diabetes. The adiponectin link concentrated in men: strong for them, absent for women. The authors read sleep fragmentation as a plausible route to the metabolic troubles of later life, and call for trials to test whether repairing sleep repairs the signals.
Catalog record
| CREATOR | Yiwei Yue, Zhikui Wei, Jill Rabinowitz, Chee Chia, Toshiko Tanaka, Eleanor Simonsick, Luigi Ferrucci, Adam Spira |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |