AGE EFFECTS ON WHITE MATTER TOPOLOGY IN OLDER ADULTS AT HIGH RISK OF ALZHEIMER’S DISEASE
Meishan Ai, Emma Tinney, Charles Hillman, Nathan Spreng, Arthur Kramer, Maiya Geddes, PREVENT-AD Research Group · 2023
Read AGE EFFECTS ON WHITE MATTER TOPOLOGY IN OLDER ADULTS AT HIGH RISK OF ALZHEIMER’S DISEASE by Meishan Ai, Emma Tinney, Charles Hillman, Nathan Spreng, Arthur Kramer, Maiya Geddes, PREVENT-AD Research Group (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10737206.txt.
Description
Meishan Ai and co-authors mapped how aging reshapes brain wiring in adults at high risk of Alzheimer's disease, in a 2023 study. All 153 volunteers were healthy in mind but had a close relative with the disease. The team built wiring maps from brain scans and gave tests of speed, switching, and word memory.
Older age went with more divided, sparser wiring networks and hubs of greater traffic. Older adults also took longer on the switching test and recalled fewer words. Schooling and test scores were weighed beside the wiring traits. The work adds detail on how the brain's white matter ages before symptoms in those at high risk.
Catalog record
| CREATOR | Meishan Ai, Emma Tinney, Charles Hillman, Nathan Spreng, Arthur Kramer, Maiya Geddes, PREVENT-AD Research Group |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |