SENNET CONSORTIUM: OPPORTUNITIES AND CHALLENGES

Laura Niedernhofer · 2023

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Description

Laura Niedernhofer introduces the SenNet consortium, a national program set up to find and describe senescent cells across the human lifespan. Senescent cells, which have stopped dividing, are implicated in most age-related chronic diseases and in the aging sped up by disease treatments. Drugs that clear them are already in trials.

The network joins labs worldwide to benchmark tools and align with other mapping efforts, and it added mouse mapping to use genetic tricks. Products will include shared naming, new biomarkers, and public four-dimensional atlases for many organs. Challenges include the lack of a specific marker for these cells and scant knowledge of what triggers senescence in the body. New single-cell and spatial tools are central to the plan.

Catalog record

CREATORLaura Niedernhofer
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10736276

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