Versatile Ultrasound-Compatible Microfluidic Platform for In Vitro Microvasculature Flow Research and Imaging Optimization
Tamar Mano, Tal Grutman, Tali Ilovitsh · 2023
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Description
Tamar Mano, Tal Grutman, and Tali Ilovitsh published a 2023 study presenting a new laboratory platform for imaging blood flow in tiny vessels. Ultrasound localization microscopy creates super-resolved maps of microvasculature by tracking injected microbubbles across thousands of fast image frames. Testing the technique requires artificial vessel networks that work with ultrasound.
The team built phantoms from gelatin, shaped like microfluidic devices, that mimic small blood vessels in a controlled and reproducible way. The networks can be made with complex layouts and fine channel sizes. Researchers can run microbubbles through them to study flow and distribution and to optimize imaging settings. Such phantoms help turn a promising imaging method into a reliable tool for studying small-vessel disease.
Catalog record
| CREATOR | Tamar Mano, Tal Grutman, Tali Ilovitsh |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |