Editorial: Editors’ showcase 2022-2023: insights in nuclear organization and dynamics
Eric C. Schirmer · 2023
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Description
Eric Schirmer introduces an editors' showcase for a journal section on how the cell nucleus is organized and how it moves. The editorial walks through the highlighted papers. One team found a new splice form of a known gene switch, SATB1, which gathers into droplets under chemical control, binds non-coding RNA, and even steers its own splicing. Its extra piece carries a prion-like stretch that strengthens the droplet behavior, and cancer data tie the variant to better outcomes.
A second highlighted review covers chromosome conformation capture, the family of methods that maps how DNA folds in 3D and exposes structural swaps behind cancers. Schirmer frames both works as signs of a fast-moving field, noting that even a protein studied for twenty-five years can still hide a new form. The showcase samples the section's breadth for new readers.
Catalog record
| CREATOR | Eric C. Schirmer |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 6 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |