Intravital imaging of the functions of immune cells in the tumor microenvironment during immunotherapy
Xuwen Peng, Yuke Wang, Jie Zhang, Zhihong Zhang, Shuhong Qi · 2023
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Description
Xuwen Peng and four co-authors review intravital imaging, a window into living tumors during immunotherapy. Their review appeared in twenty twenty-three. Cancer immunotherapy works through immune cells moving and acting inside tissue, and flat snapshots miss that motion.
The technique watches cells in real time, in place, with fine detail and multiple colors at once. The authors walk through the full workflow: labeling tricks, optical windows cut into tissue, and ways to analyze the footage. Recent studies show immune cells hunting, pausing, and killing as treatment unfolds. Seeing those dynamics helps explain why therapies succeed or fail. The review argues this living view is now essential for improving immunotherapy design.
Catalog record
| CREATOR | Xuwen Peng, Yuke Wang, Jie Zhang, Zhihong Zhang, Shuhong Qi |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |