Evaluating the long-term biological stability of cytokine biomarkers in ocular fluid samples

Tina Felfeli, Jeff Park, Bret Nestor, Filiberto Altomare, Amandeep S Rai, Efrem D Mandelcorn, David R Chow, David T Wong · 2023

Read Evaluating the long-term biological stability of cytokine biomarkers in ocular fluid samples by Tina Felfeli, Jeff Park, Bret Nestor, Filiberto Altomare, Amandeep S Rai, Efrem D Mandelcorn, David R Chow, David T Wong (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10729172.txt.

Description

Tina Felfeli and co-authors test how long cytokine markers stay stable in stored eye fluid samples. Reliable samples are the bedrock of biomarker research. Freezing and thawing can quietly degrade the signals.

Fluid came from the front and back of twenty-five eyes. Samples waited in deep freeze for set spans. Levels of twenty-seven cytokines were measured at each point. Up to three freeze-thaw cycles were also tried. Four markers fell clearly with storage time. The drop began as early as three months in. Other markers held steadier across the full span. The results set handling rules for eye biobanks and labs and clinics and wards alike.

Catalog record

CREATORTina Felfeli, Jeff Park, Bret Nestor, Filiberto Altomare, Amandeep S Rai, Efrem D Mandelcorn, David R Chow, David T Wong
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10729172

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