Study protocol for a prospective, multicentre, phase II trial on endoscopic treatment using two fully covered self-expandable metallic stents for benign strictures after hepaticojejunostomy
Yuki Kawasaki, Susumu Hijioka, Yoshikuni Nagashio, Akihiro Ohba, Yuta Maruki, Kotaro Takeshita, Tetsuro Takasaki, Shin Yagi, Daiki Agarie, Yuya Hagiwara, Hidenobu Hara, Kohei Okamoto, Daiki Yamashige, Souma Fukuda, Masaru Kuwada, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Takuji Okusaka · 2023
Read Study protocol for a prospective, multicentre, phase II trial on endoscopic treatment using two fully covered self-expandable metallic stents for benign strictures after hepaticojejunostomy by Yuki Kawasaki, Susumu Hijioka, Yoshikuni Nagashio, Akihiro Ohba, Yuta Maruki, Kotaro Takeshita, Tetsuro Takasaki, Shin Yagi, Daiki Agarie, Yuya Hagiwara, Hidenobu Hara, Kohei Okamoto, Daiki Yamashige, Souma Fukuda, Masaru Kuwada, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Takuji Okusaka (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10729169.txt.
Description
Yuki Kawasaki and co-authors planned a stent trial for bile duct narrowing in two thousand twenty-three. Surgery joining bowel to bile duct can scar shut. Endoscopic stents reopen the narrowed join. Short-term success is high, but renarrowing is common. Two covered metal stents form their new approach. The multicentre phase two trial is prospective.
The main measure is staying open at twelve months. Past trials only used immediate resolution rates. Long-term openness is the honest test here. The protocol is nicknamed the saddle-cross study. Several Japanese centers will enroll patients. Safety and procedure success are tracked alongside. A positive result could change standard care. Patients would face fewer repeat procedures.
Catalog record
| CREATOR | Yuki Kawasaki, Susumu Hijioka, Yoshikuni Nagashio, Akihiro Ohba, Yuta Maruki, Kotaro Takeshita, Tetsuro Takasaki, Shin Yagi, Daiki Agarie, Yuya Hagiwara, Hidenobu Hara, Kohei Okamoto, Daiki Yamashige, Souma Fukuda, Masaru Kuwada, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Takuji Okusaka |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |