Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial

Sarah Pyne, Tracey H Sach, Megan Lawrence, Susanne Renz, Zina Eminton, Beth Stuart, Kim S Thomas, Nick Francis, Irene Soulsby, Karen Thomas, Natalia V Permyakova, Matthew J Ridd, Paul Little, Ingrid Muller, Jacqui Nuttall, Gareth Griffiths, Alison M Layton, Miriam Santer · 2023

Read Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial by Sarah Pyne, Tracey H Sach, Megan Lawrence, Susanne Renz, Zina Eminton, Beth Stuart, Kim S Thomas, Nick Francis, Irene Soulsby, Karen Thomas, Natalia V Permyakova, Matthew J Ridd, Paul Little, Ingrid Muller, Jacqui Nuttall, Gareth Griffiths, Alison M Layton, Miriam Santer (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10729081.txt.

Description

Sarah Pyne and a large team of co-authors published a 2023 economic study on whether spironolactone is good value for treating persistent acne in adult women. The drug, long used for blood pressure, is an alternative to oral antibiotics for acne. The study ran alongside a randomized trial in British primary and secondary care.

Women with facial acne that warranted oral treatment received either the drug plus usual creams, or a placebo plus creams, for 24 weeks. The dose rose halfway through the trial. Costs and quality of life were tracked from the health service's point of view. The analysis computed the cost per quality adjusted life year gained, the standard yardstick for value. A cost effectiveness view over the trial period completes the picture for prescribers and payers.

Catalog record

CREATORSarah Pyne, Tracey H Sach, Megan Lawrence, Susanne Renz, Zina Eminton, Beth Stuart, Kim S Thomas, Nick Francis, Irene Soulsby, Karen Thomas, Natalia V Permyakova, Matthew J Ridd, Paul Little, Ingrid Muller, Jacqui Nuttall, Gareth Griffiths, Alison M Layton, Miriam Santer
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10729081

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