Non‐lesional white matter in relapsing–remitting multiple sclerosis assessed by multicomponent T2 relaxation
Pietro Bontempi, Umberto Rozzanigo, Sabrina Marangoni, Elena Fogazzi, Daniele Ravanelli, Lucia Cazzoletti, Bruno Giometto, Paolo Farace · 2023
Read Non‐lesional white matter in relapsing–remitting multiple sclerosis assessed by multicomponent T2 relaxation by Pietro Bontempi, Umberto Rozzanigo, Sabrina Marangoni, Elena Fogazzi, Daniele Ravanelli, Lucia Cazzoletti, Bruno Giometto, Paolo Farace (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10726908.txt.
Description
Pietro Bontempi and co-authors study white matter that looks normal in relapsing-remitting multiple sclerosis, using multicomponent T2 relaxation imaging. Their 2023 study aims to probe tissue that lies outside the visible lesions.
Twenty stable patients had 1.5 tesla MRI scans with FLAIR, T1-weighted, and multi-echo T2 sequences. Lesions were segmented from FLAIR images, and white matter volumes came from the T1 scans. Non-lesional white matter was what remained after lesion volumes were removed. The multi-echo data were split into myelin water, intra-extracellular water, and free water. Links between these fractions and lesion traits were then tested for signs of hidden damage.
Catalog record
| CREATOR | Pietro Bontempi, Umberto Rozzanigo, Sabrina Marangoni, Elena Fogazzi, Daniele Ravanelli, Lucia Cazzoletti, Bruno Giometto, Paolo Farace |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |