Identification of age‐specific biomarkers of spinal cord injury: A bioinformatics analysis of young and aged mice models
Wei Miao, Zheng Su, Huilin Cheng · 2023
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Description
Wei Miao, Zheng Su, and Huilin Cheng hunt age-linked marker genes for spinal cord injury in mice. Their 2023 study uses public gene data from young and aged injured mice, plus control mice. Recovery after cord injury fades with age, and the gene basis for that gap is unclear.
Thousands of genes changed activity after injury in both age groups, with more changes in aged mice. Enriched pathways split by age too, though one swelling pathway lit up in both. Network analysis flags hub genes and a key module tied to injury traits. Pathway charts round out the candidate list. The results offer age-specific markers that could guide care tuned to young versus older patients.
Catalog record
| CREATOR | Wei Miao, Zheng Su, Huilin Cheng |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |