Modbed track: Visualization of modified bases in single-molecule sequencing

Daofeng Li, Xiaoyu Zhuo, Jessica K. Harrison, Shane Liu, Ting Wang · 2023

Read Modbed track: Visualization of modified bases in single-molecule sequencing by Daofeng Li, Xiaoyu Zhuo, Jessica K. Harrison, Shane Liu, Ting Wang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10726485.txt.

Description

Daofeng Li and co-authors present a 2023 tool for viewing chemical marks on DNA in long read sequencing. Long reads can now spot base modifications with good accuracy, which opens a fresh window on the epigenome. Genome browsers, though, lacked a way to show those marks well.

The team adds a track type, called modbed, to the WashU Epigenome Browser. The track shows mark detail read by read and also pooled marks across one or many molecules, at zoom levels that shift on the fly. Files can be uploaded as a local track or viewed by a public link at no cost. The tool aims to make epigenome data easy to explore.

Catalog record

CREATORDaofeng Li, Xiaoyu Zhuo, Jessica K. Harrison, Shane Liu, Ting Wang
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10726485

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