Therapeutic Effects of Mesenchymal/Stromal Stem Cells and Their Derived Extracellular Vesicles in Rheumatoid Arthritis
Dimitrios Tsiapalis, Achilleas Floudas, Tobias Tertel, Verena Boerger, Bernd Giebel, Douglas J Veale, Ursula Fearon, Lorraine O’Driscoll · 2023
Read Therapeutic Effects of Mesenchymal/Stromal Stem Cells and Their Derived Extracellular Vesicles in Rheumatoid Arthritis by Dimitrios Tsiapalis, Achilleas Floudas, Tobias Tertel, Verena Boerger, Bernd Giebel, Douglas J Veale, Ursula Fearon, Lorraine O’Driscoll (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10726408.txt.
Description
Dimitrios Tsiapalis and co-authors report a 2023 lab study on joint disease with long-term swelling. Current drugs for this disease do not fully stop swelling or joint damage. Stem-like cells from body tissue can calm the defense system. Tiny packets shed by those cells may carry the same calm effect. The team tested both the cells and their packets on patient cells.
Packets came from plain cells and from cells primed with a defense signal. On patient helper T cells, packets from primed cells cut more key swelling signals. The team also tested packets on joint lining cells from patients. The results suggest packets could aid care without using whole live cells. The work is at lab stage, not a patient trial. Still, it marks which packet type looks strongest for the next steps toward trials.
Catalog record
| CREATOR | Dimitrios Tsiapalis, Achilleas Floudas, Tobias Tertel, Verena Boerger, Bernd Giebel, Douglas J Veale, Ursula Fearon, Lorraine O’Driscoll |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |