Development and Validation of a Prognostic Model for Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma Based on Preoperative Serum Prealbumin

Lin Xu, Dongxu Zhao, Pengcheng Tian, Jiaan Ding, Zhengyu Jiang, Guanyin Ni, Zhongheng Hou, Caifang Ni · 2023

Read Development and Validation of a Prognostic Model for Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma Based on Preoperative Serum Prealbumin by Lin Xu, Dongxu Zhao, Pengcheng Tian, Jiaan Ding, Zhengyu Jiang, Guanyin Ni, Zhongheng Hou, Caifang Ni (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10725684.txt.

Description

Lin Xu and co-authors build a prediction tool for liver cancer patients who get a targeted chemo treatment, in a 2023 study. The treatment sends chemotherapy through an artery into tumours that cannot be removed by surgery. The team test whether a blood protein measured before treatment, called prealbumin, helps predict survival.

More than seven hundred patients from three centres in Suzhou were split into training and validation groups. Seven factors, including cancer stage, liver scarring, tumour size and count, and the protein level, independently predicted survival. A scoring chart built from them separated low-risk from high-risk patients clearly and beat four standard staging systems. Checks showed its predictions matched real outcomes well. The authors offer the chart as a tool for personal treatment choices in this cancer.

Catalog record

CREATORLin Xu, Dongxu Zhao, Pengcheng Tian, Jiaan Ding, Zhengyu Jiang, Guanyin Ni, Zhongheng Hou, Caifang Ni
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10725684

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