Epithelioid Subtype Gastrointestinal Stromal Tumors of Stomach in an Endoscopic Biopsy: A Potential Diagnostic Pitfall

Wenfeng Xu, Hao Tang, Ying Chen, Jiashuang Wang, Zhongjiao Chen, Yujuan Xu, Deyu Guo · 2023

Read Epithelioid Subtype Gastrointestinal Stromal Tumors of Stomach in an Endoscopic Biopsy: A Potential Diagnostic Pitfall by Wenfeng Xu, Hao Tang, Ying Chen, Jiashuang Wang, Zhongjiao Chen, Yujuan Xu, Deyu Guo (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10725679.txt.

Description

Wenfeng Xu, Hao Tang, Ying Chen, and four colleagues report a four-year wrong diagnosis in this two thousand twenty-three case report. A sixty-five-year-old man carried a stomach tumor diagnosed as adenocarcinoma and received chemotherapy combined with PD-L1 immunotherapy. Doctors believed it worked, yet the tumor never shrank and his symptoms never truly improved. A repeat biopsy at the authors' hospital, checked by form, markers, and genome sequencing, gave a different answer: an epithelioid gut stromal tumor.

Epithelioid stromal tumors make up about twenty percent of these tumors and mimic poorly differentiated adenocarcinoma and lymphoma under the microscope, a known diagnostic trap. The authors draw two lessons. Tissue doctors should lean on site, form, and the right markers for this tumor family. Clinicians should judge response by symptoms and lab proof rather than trusting a tissue label too far.

Catalog record

CREATORWenfeng Xu, Hao Tang, Ying Chen, Jiashuang Wang, Zhongjiao Chen, Yujuan Xu, Deyu Guo
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE17 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10725679

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