Green Nanotechnology of Yucca filamentosa- Phytochemicals-Functionalized Gold Nanoparticles—Antitumor Efficacy Against Prostate and Breast Cancers

Velaphi C Thipe, Ananya Jatar, Alice Raphael Karikachery, Kavita K Katti, Kattesh V Katti · 2023

Read Green Nanotechnology of Yucca filamentosa- Phytochemicals-Functionalized Gold Nanoparticles—Antitumor Efficacy Against Prostate and Breast Cancers by Velaphi C Thipe, Ananya Jatar, Alice Raphael Karikachery, Kavita K Katti, Kattesh V Katti (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10723618.txt.

Description

Velaphi Thipe and co-authors make gold nanoparticles from yucca plant extract and test them on cancers in a 2023 study. Green synthesis skips harsh chemicals: the plant's own compounds both build the particles and coat them. A gum arabic version added stability.

The particles came out small, round, and evenly sized, with surface charges suited to staying suspended. In lab dishes they killed prostate and breast cancer cells by triggering early and late cell death, while sparing normal cells. They also shifted immune signals, raising anti-tumor messengers and lowering pro-tumor ones. Uniquely, the particles targeted the macrophage cells that help tumors grow. The authors present the agents as a plant-based nanomedicine candidate.

Catalog record

CREATORVelaphi C Thipe, Ananya Jatar, Alice Raphael Karikachery, Kavita K Katti, Kattesh V Katti
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE57 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10723618

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