Improved diagnostic sensitivity of human strongyloidiasis using point-of-care mixed recombinant antigen-based immunochromatography
Patcharaporn Boonroumkaew, Lakkhana Sadaow, Penchom Janwan, Rutchanee Rodpai, Oranuch Sanpool, Punyisa Buadee, Chanida Suprom, Tongjit Thanchomnang, Pewpan M Intapan, Wanchai Maleewong · 2023
Read Improved diagnostic sensitivity of human strongyloidiasis using point-of-care mixed recombinant antigen-based immunochromatography by Patcharaporn Boonroumkaew, Lakkhana Sadaow, Penchom Janwan, Rutchanee Rodpai, Oranuch Sanpool, Punyisa Buadee, Chanida Suprom, Tongjit Thanchomnang, Pewpan M Intapan, Wanchai Maleewong (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10723528.txt.
Description
Patcharaporn Boonroumkaew and co-authors build, in 2023, a rapid point-of-care test for a neglected worm infection that can turn deadly in people with weak immunity. Diagnosis by stool exam misses many cases, so antibody tests matter. The team made strip tests from two worm proteins, separately and mixed.
Serum came from healthy people, proven patients, and people with other parasites. The mixed test won, catching ninety-five percent of cases while keeping about ninety percent specificity. Single-protein strips were weaker on both counts. The authors recommend the mixed strip to support diagnosis, screen people at risk in endemic areas, and power large surveys without extra lab gear.
Catalog record
| CREATOR | Patcharaporn Boonroumkaew, Lakkhana Sadaow, Penchom Janwan, Rutchanee Rodpai, Oranuch Sanpool, Punyisa Buadee, Chanida Suprom, Tongjit Thanchomnang, Pewpan M Intapan, Wanchai Maleewong |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |