Roles of inflammatory cell infiltrate in periprosthetic osteolysis
Isidora Panez-Toro, Dominique Heymann, François Gouin, Jérôme Amiaud, Marie-Françoise Heymann, Luis A. Córdova · 2023
Read Roles of inflammatory cell infiltrate in periprosthetic osteolysis by Isidora Panez-Toro, Dominique Heymann, François Gouin, Jérôme Amiaud, Marie-Françoise Heymann, Luis A. Córdova (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10722268.txt.
Description
Isidora Panez-Toro and co-authors review the immune cells involved when bone breaks down around joint implants, in a 2023 article. Wear particles from an implant can trigger inflammation that eats away bone and loosens the joint, a process called osteolysis. The classic account blames one family of immune cells and the bone-eating cells they activate.
Newer reports, including the authors' own data, show a wider mix of cells in tissue taken from around failed implants. Alongside the classic cells, they discuss helper and killer T cells and antibody-making B cells found near plastic and metal particles. The review adds these cells to the picture of implant loosening. That wider view may point to new ways to prevent or treat the problem.
Catalog record
| CREATOR | Isidora Panez-Toro, Dominique Heymann, François Gouin, Jérôme Amiaud, Marie-Françoise Heymann, Luis A. Córdova |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |