Dermatophagoides farinae microRNAs released to external environments via exosomes regulate inflammation-related gene expression in human bronchial epithelial cells
Kaiyue He, Ting Yang, Jinyan Yu, Xiao Zang, Shangde Jiang, Shuyue Xu, Jiaxi Liu, Zuyu Xu, Wei Wang, Shanchao Hong · 2023
Read Dermatophagoides farinae microRNAs released to external environments via exosomes regulate inflammation-related gene expression in human bronchial epithelial cells by Kaiyue He, Ting Yang, Jinyan Yu, Xiao Zang, Shangde Jiang, Shuyue Xu, Jiaxi Liu, Zuyu Xu, Wei Wang, Shanchao Hong (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10722260.txt.
Description
Kaiyue He and a team report in a 2023 study that tiny bits of mite RNA can ride in small sacs. Once inside human airway cells, the bits change how the cells act. The mite is a house dust mite. It is a well known cause of allergy. Past work put the blame on mite proteins. Little was known about these small RNA bits. Mites may send them out in packed form.
The team read the small RNA in the mites. It did the same for the shed sacs and the growth fluid. A lab test found the same RNA in house dust. Airway cells grown in the lab took in the mite sacs. The study tracks how the mite RNA shifts genes tied to swelling. It points to a way mites may spark allergy across species lines.
Catalog record
| CREATOR | Kaiyue He, Ting Yang, Jinyan Yu, Xiao Zang, Shangde Jiang, Shuyue Xu, Jiaxi Liu, Zuyu Xu, Wei Wang, Shanchao Hong |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |