Association of plasma amyloid-β oligomerization with theta/beta ratio in older adults

Heewon Bae, Min Ju Kang, Sang-Won Ha, Da-Eun Jeong, Kiwon Lee, Seungui Lim, Jin-Young Min, Kyoung-Bok Min · 2023

Read Association of plasma amyloid-β oligomerization with theta/beta ratio in older adults by Heewon Bae, Min Ju Kang, Sang-Won Ha, Da-Eun Jeong, Kiwon Lee, Seungui Lim, Jin-Young Min, Kyoung-Bok Min (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10722169.txt.

Description

A blood marker of amyloid buildup relates to a brain-wave ratio in older adults, Heewon Bae and co-authors report in a 2023 study. Oligomeric amyloid-beta in plasma is a promising candidate marker for Alzheimer's disease diagnosis. Electroencephalography is a potential tool for early detection. Whether EEG power ratios reflect amyloid burden, a primary mechanism behind cognitive impairment, was the open question behind the work.

Over five hundred adults aged sixty and older underwent EEG recording and a plasma test quantifying the oligomer marker. Participants were split into high and low marker groups by a cutoff value. The theta/beta ratio named in the title was compared between groups, alongside the theta/alpha ratio. Readers get a step toward cheap, non-invasive screening signals for Alzheimer's risk.

Catalog record

CREATORHeewon Bae, Min Ju Kang, Sang-Won Ha, Da-Eun Jeong, Kiwon Lee, Seungui Lim, Jin-Young Min, Kyoung-Bok Min
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10722169

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