Efficacy and mechanism of Shenqi Compound in inhibiting diabetic vascular calcification
Chan Yang, Ziyan Xie, Hanyu Liu, Xueru Wang, Zehua Zhang, Lian Du, Chunguang Xie · 2023
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Description
Chan Yang and co-authors test a traditional herbal compound against blood vessel hardening in diabetic rats in a 2023 study. The compound has been used for decades against diabetes and its complications, but mainly on the strength of experience. Vessel calcification, where calcium salts crust artery walls, is one such complication.
Diabetic rats treated with the compound showed far less vessel calcification than untreated diabetic rats. Lab work traced the gain to several routes: steadier sugar and fat levels, vessel wall cells kept from turning bone-like, less cell death and inflammation, and changes in a growth signaling pathway. Tissue and gene tests backed the picture. The study gives the old remedy a measured, mechanism-based footing.
Catalog record
| CREATOR | Chan Yang, Ziyan Xie, Hanyu Liu, Xueru Wang, Zehua Zhang, Lian Du, Chunguang Xie |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |