Unraveling the genome of Bacillus velezensis MEP218, a strain producing fengycin homologs with broad antibacterial activity: comprehensive comparative genome analysis

Daniela Medeot, Analía Sannazzaro, María Julia Estrella, Gonzalo Torres Tejerizo, Bruno Contreras-Moreira, Mariano Pistorio, Edgardo Jofré · 2023

Read Unraveling the genome of Bacillus velezensis MEP218, a strain producing fengycin homologs with broad antibacterial activity: comprehensive comparative genome analysis by Daniela Medeot, Analía Sannazzaro, María Julia Estrella, Gonzalo Torres Tejerizo, Bruno Contreras-Moreira, Mariano Pistorio, Edgardo Jofré (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10719345.txt.

Description

Daniela Medeot and six co-authors read the full genome of a helpful soil bacterium in a 2023 study. The strain makes a family of ring shaped compounds that kill a broad range of germs. Reading its genes could show how it builds those compounds and where it sits in its family tree.

The genome runs near four million letters with about thirty five hundred genes. Family analysis placed the strain in the Bacillus velezensis species. Eleven gene clusters build side compounds, from the germ killing rings to scents and germ guards. Genes for plant food freeing enzymes also showed up. Dish tests confirmed the strain's rings halt gut and skin germs, among others.

Catalog record

CREATORDaniela Medeot, Analía Sannazzaro, María Julia Estrella, Gonzalo Torres Tejerizo, Bruno Contreras-Moreira, Mariano Pistorio, Edgardo Jofré
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10719345

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