Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer

Farhad Sheikhnia, Vahid Rashidi, Hossein Maghsoudi, Maryam Majidinia · 2023

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Description

Farhad Sheikhnia, Vahid Rashidi, Hossein Maghsoudi, and Maryam Majidinia review a black seed compound as a possible helper against colon and rectal cancer. The compound, thymoquinone, comes from Nigella sativa and has a long history in traditional medicine for many ailments. The review gathers dish and animal studies of its action on colorectal tumors. Across those studies the compound slowed cancer cells through several pathways.

Paired with standard anti-cancer drugs, it strengthened their effect while softening their side effects in the reported work. The authors call it a promising partner therapy rather than a stand-alone cure. Big gaps remain: its exact molecular targets and pathways are not yet pinned down. More work, they argue, could turn the compound into a tool against drug resistance, one of the hardest problems in treating this cancer.

Catalog record

CREATORFarhad Sheikhnia, Vahid Rashidi, Hossein Maghsoudi, Maryam Majidinia
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10717210

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