Construction of a ceRNA regulatory network to explore potential pathogenesis mechanisms involved in human hepatocellular carcinoma
Yicun Liu, Zhixing Dong, WeiJie Chen, Lin Chen, Linling Ju, Weihua Cai, Xi Luo, Zhaolian Bian · 2023
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Description
Yicun Liu and seven co-authors build a competing RNA network to probe how liver cancer forms, centered on circular RNAs that sponge small RNAs. Liver cancer is a top cause of cancer death worldwide. The study came out in twenty twenty-three.
Profile scans found thousands of changed circular RNAs in tumor tissue. The top risers were checked in a fresh patient group by a gene copy test, and five were picked for network work. Database hunts traced their down stream small RNAs and target messages, which formed the network maps. Five chains in the network link to worse outlook for patients, the authors report.
Catalog record
| CREATOR | Yicun Liu, Zhixing Dong, WeiJie Chen, Lin Chen, Linling Ju, Weihua Cai, Xi Luo, Zhaolian Bian |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |