Antiseizure Effects of Peganum harmala L. and Lavandula angustifolia

Zahra Rahimian, SeyedHassan Sadrian, Mina Shahisavandi, Hadi Aligholi, Mohammad M. Zarshenas, Alireza Abyar, Zahra Zeraatpisheh, Ali A. Asadi-Pooya · 2023

Read Antiseizure Effects of Peganum harmala L. and Lavandula angustifolia by Zahra Rahimian, SeyedHassan Sadrian, Mina Shahisavandi, Hadi Aligholi, Mohammad M. Zarshenas, Alireza Abyar, Zahra Zeraatpisheh, Ali A. Asadi-Pooya (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10715855.txt.

Description

Zahra Rahimian and co-authors test two traditional herbs against seizures in mice, in a 2023 study. Extracts of Syrian rue seeds and lavender tops were given before a chemical that reliably triggers convulsions, across a wide range of doses, with a standard sedative as comparison. The team timed how long seizures took to start and how long they lasted, and checked survival.

Syrian rue worked at a middling dose, delaying and shortening seizures and protecting nine in ten mice. Lavender helped at its higher doses too. Two blocker drugs failed to undo either herb's effect, leaving the mechanism open. The results back the herbs' folk reputation with lab evidence.

Catalog record

CREATORZahra Rahimian, SeyedHassan Sadrian, Mina Shahisavandi, Hadi Aligholi, Mohammad M. Zarshenas, Alireza Abyar, Zahra Zeraatpisheh, Ali A. Asadi-Pooya
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE21 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10715855

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