Prognostic and Immune Infiltration Analysis of Transaldolase 1 (TALDO1) in Hepatocellular Carcinoma
Kedan Cen, Caide Lu · 2023
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Description
Kedan Cen and Caide Lu examine a gene called TALDO1 as a warning sign in liver cancer. Their 2023 study starts from a clue: lacking this gene has been linked to the same cancer. Whether the gene's activity level predicts how patients fare was still unclear.
Using tumor data from two large public sets, they found the gene runs higher in cancer tissue than in healthy tissue. High levels tracked with worse grade and shorter survival, even after other factors were counted. Lab tests added weight: turning the gene down slowed the growth and spread of liver cancer cells. The gene seems to act through known growth pathways and to damp immune response in tumors.
Catalog record
| CREATOR | Kedan Cen, Caide Lu |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |