Insights into myopic choroidal neovascularization based on quantitative proteomics analysis of the aqueous humor
Huimin Yu, Zheng Zhong, Yin Zhao, Huan Luo, Jinfu Sun, Ruohong Wang, Xian Zhang, Xufang Sun · 2023
Read Insights into myopic choroidal neovascularization based on quantitative proteomics analysis of the aqueous humor by Huimin Yu, Zheng Zhong, Yin Zhao, Huan Luo, Jinfu Sun, Ruohong Wang, Xian Zhang, Xufang Sun (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10714574.txt.
Description
Huimin Yu and co-authors read the fluid inside the eye for clues to a blinding form of nearsightedness. In pathologic myopia, new vessels sprout under the retina and leak. The team profiled hundreds of proteins in eye fluid from patients graded by damage type. Wasting and vessel growth lesions tracked together closely.
Both shared raised levels of a support cell protein and immune complement factors. One signaling pathway stood out between the vessel group and controls. Seven candidate markers emerged, including the support protein and a growth receptor. The authors argue that wasting changes set the stage for vessel growth, and the markers could guide early checks.
Catalog record
| CREATOR | Huimin Yu, Zheng Zhong, Yin Zhao, Huan Luo, Jinfu Sun, Ruohong Wang, Xian Zhang, Xufang Sun |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |