Retrospective evaluation of prognosis and survival with various immunosuppressants in 82 dogs diagnosed with meningoencephalitis of unknown etiology (2010–2021)
So-Hee Kim, Ye-In Oh, Su-Min Park, Ju Hyun An, Tae-Hee Kim, Sung-Soo Kim, Jae-Gon Ah, Kyoung-Won Seo, Hwa-Young Youn · 2023
Read Retrospective evaluation of prognosis and survival with various immunosuppressants in 82 dogs diagnosed with meningoencephalitis of unknown etiology (2010–2021) by So-Hee Kim, Ye-In Oh, Su-Min Park, Ju Hyun An, Tae-Hee Kim, Sung-Soo Kim, Jae-Gon Ah, Kyoung-Won Seo, Hwa-Young Youn (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10714563.txt.
Description
So-Hee Kim and co-authors compare immune-suppressing drugs in dogs with brain inflammation of unknown cause, in a 2023 veterinary study. The disease, called MUE, stems from abnormal autoimmune attack on the brain and spinal cord. Dogs receive steroids plus one of several add-on drugs, but which add-on serves best was unclear.
The team reviewed records of eighty-two dogs treated between 2010 and 2021. Overall median survival came to about two years. Leflunomide dogs lived longest and responded relatively well, though a few developed serious anemia. A two-drug combination fared worst. Survival and response clearly depended on the add-on drug chosen, giving vets comparative evidence for a disease with few trials.
Catalog record
| CREATOR | So-Hee Kim, Ye-In Oh, Su-Min Park, Ju Hyun An, Tae-Hee Kim, Sung-Soo Kim, Jae-Gon Ah, Kyoung-Won Seo, Hwa-Young Youn |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |