Rendering protein mutation movies with MutAmore
Konstantin Weissenow, Burkhard Rost · 2023
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Description
Konstantin Weissenow and Burkhard Rost present a tool that turns protein mutations into movies, in this 2023 paper. Structure prediction now gives reliable protein shapes, shifting focus to how changes alter them. Judging many variant shapes by eye is hard.
Their tool builds every single-letter variant of a protein, predicts each shape with current models, then renders a color-coded 3D animation of the set. Users can also feed in variants from lab structures. The movie gives a quick, visual sense of the mutation landscape. The authors aim the tool at the post-AlphaFold study of shape change.
Catalog record
| CREATOR | Konstantin Weissenow, Burkhard Rost |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |