Assessing multiple factors affecting the gut microbiome structure of very preterm infants
Wenlong Xiu, Jiajia Lin, Yanhua Hu, Heng Tang, Shuangchan Wu, Changyi Yang · 2023
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Description
Wenlong Xiu and co-authors present a 2023 study of what shapes the gut microbes of very preterm infants. A baby born before thirty-two weeks assembles its gut community under hospital conditions, and that assembly steers immune development. The relative weight of birth route, antibiotics, and feeding was unclear.
Stool from sixty-four such infants was sequenced across the first weeks of life. Proteobacteria dominated early in both cesarean and vaginal births, then gave way to Firmicutes after week one in the vaginal group. When mothers had antibiotics, Proteobacteria stayed on top longer; without them, Firmicutes led. Breastfed and mixed-fed babies kept high Proteobacteria shares, while formula-fed babies flipped to Firmicutes after the first week. The authors say early care choices leave fingerprints on the microbiome.
Catalog record
| CREATOR | Wenlong Xiu, Jiajia Lin, Yanhua Hu, Heng Tang, Shuangchan Wu, Changyi Yang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |