Evaluation of Cytotoxicity of the Methanolic Extract of Red Sea Marine Sponge Xestospongia Testudinaria and Its Related Compounds Against MCF-7 Human Breast Cancer Cells
Faris A Alkhilaiwi, Sana A Fadil, Fadwa A Aljoud, Ahmed R Yonbawi, Abrar Ashi, Rawan H Hareeri, Sherin Bakhashab, Ahmad M Alamri, Ahmed Y Albikairi, Lamiaa A Shaala, Ali A El-Gamal, Diaa T Youssef · 2023
Read Evaluation of Cytotoxicity of the Methanolic Extract of Red Sea Marine Sponge Xestospongia Testudinaria and Its Related Compounds Against MCF-7 Human Breast Cancer Cells by Faris A Alkhilaiwi, Sana A Fadil, Fadwa A Aljoud, Ahmed R Yonbawi, Abrar Ashi, Rawan H Hareeri, Sherin Bakhashab, Ahmad M Alamri, Ahmed Y Albikairi, Lamiaa A Shaala, Ali A El-Gamal, Diaa T Youssef (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10712258.txt.
Description
Faris Alkhilaiwi and co-authors test a Red Sea sponge extract against breast cancer cells in this 2023 study. The barrel sponge holds sterols, alkaloids, and rare fats with past hints of healing power. The team asks whether its alcohol extract can slow a standard breast cancer cell line.
Cell survival fell as dose rose, with a mid-kill dose in a modest range. Treated cells showed more self-kill signals and stalled at a rest phase of the growth cycle. In a scratch test, treated cells also crept closed more slowly. The authors say the extract holds promise as a lead, while much work stands between cell tests and a drug.
Catalog record
| CREATOR | Faris A Alkhilaiwi, Sana A Fadil, Fadwa A Aljoud, Ahmed R Yonbawi, Abrar Ashi, Rawan H Hareeri, Sherin Bakhashab, Ahmad M Alamri, Ahmed Y Albikairi, Lamiaa A Shaala, Ali A El-Gamal, Diaa T Youssef |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |