Nebulized dexmedetomidine for attenuating hemodynamic response to laryngoscopy and endotracheal intubation in adult patients undergoing surgeries under general anaesthesia: a systematic review and meta-analysis of randomized controlled trials

Mayank Gupta, Rachna Rohilla, Priyanka Gupta, Hemanthkumar Tamilchelvan, Udita Joshi, Jyoti Kanwat · 2023

Read Nebulized dexmedetomidine for attenuating hemodynamic response to laryngoscopy and endotracheal intubation in adult patients undergoing surgeries under general anaesthesia: a systematic review and meta-analysis of randomized controlled trials by Mayank Gupta, Rachna Rohilla, Priyanka Gupta, Hemanthkumar Tamilchelvan, Udita Joshi, Jyoti Kanwat (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10712167.txt.

Description

Gupta and co-authors review in 2023 trials of a calming drug given as a mist before surgery. Placing a breathing tube can spike heart rate and blood pressure, which may harm weak patients. The mist form spreads over a wide surface and may avoid the slow heart rate seen with drip delivery.

The team searched six databases up to March 2023 for trials in adults under full sleep for surgery. Two reviewers screened the work on their own against set rules. Trials had to report heart rate and blood pressure around tube placement. The pooled results aim to show if the mist is safe and works well enough for routine use.

Catalog record

CREATORMayank Gupta, Rachna Rohilla, Priyanka Gupta, Hemanthkumar Tamilchelvan, Udita Joshi, Jyoti Kanwat
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10712167

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