The application of nanoparticles in theranostic systems targeting breast cancer stem cells: current progress and future challenges

Xinyu Lin, Ying Wang, Kai Fang, Zijian Guo, Nan Lin, Lihua Li · 2023

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Description

Xinyu Lin and co-authors review tiny particle systems that target breast cancer stem cells in a 2023 paper. Breast cancer has high death rates for women worldwide, and stem like cancer cells drive much of the harm. Standard drugs kill regular cancer cells, while stem cells survive, seeding resistance and spread. Killing both types is the key challenge the review addresses.

Nanotechnology offers ways to aim drugs and imaging at those stem cells, the authors survey. They sum up current uses of nanomaterials for this target and its limits. They also propose a new lipid particle that could target the stem cells through messenger RNA delivery. Readers get a progress map and a fresh design idea for a stubborn problem.

Catalog record

CREATORXinyu Lin, Ying Wang, Kai Fang, Zijian Guo, Nan Lin, Lihua Li
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10712155

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