Levocetrizine attenuates cyclophosphamide-induced lung injury through inhibition of TNF-α, IL-1β, TGF-β and MMP-9
Dalia H El-Kashef, Mona Abdel Rahim · 2023
Read Levocetrizine attenuates cyclophosphamide-induced lung injury through inhibition of TNF-α, IL-1β, TGF-β and MMP-9 by Dalia H El-Kashef, Mona Abdel Rahim (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10712110.txt.
Description
Dalia H El-Kashef and Mona Abdel Rahim tested whether an allergy drug can protect rat lungs from a harsh cancer drug, in a study published in 2023. The cancer drug is used worldwide but can badly damage the lungs. The allergy drug is known to calm swelling and allergic responses, which made it a candidate shield.
Rats given the cancer drug alone showed clear lung harm: more swelling signals, more damage markers, and worse tissue under the microscope. Rats that also received the allergy drug for two weeks, starting a week before, showed much less of each harm. The authors credit the drug's mix of calming, protective, and anti-scarring effects. The work is early, animal-only evidence, but it points to a possible guard for patients who need the cancer drug.
Catalog record
| CREATOR | Dalia H El-Kashef, Mona Abdel Rahim |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |