Thrombotic thrombocytopenic purpura presenting as stroke mimics with normal diffusion-weighted MRI

Ziyi Zhang, Miao He · 2023

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Description

Ziyi Zhang and Miao He present a blood disorder hiding behind stroke symptoms, in a 2023 case report. A sixty-five-year-old man arrived with sudden slurred speech, facial droop, and one-sided paralysis, the classic picture of acute ischemic stroke. Yet his CT and MRI showed no new brain lesion at all.

Blood tests instead revealed thrombotic thrombocytopenic purpura: very low platelets, mild anemia, raised breakdown markers, and a severely reduced ADAMTS-13 enzyme level. Plasma exchange treatment cleared his symptoms quickly. The authors warn emergency clinicians to think of this rare, fatal clotting disease whenever stroke-like signs arrive with low platelets, whether or not scans show damage.

Catalog record

CREATORZiyi Zhang, Miao He
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE10 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10712053

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