Overall survival of patients with cHL who progress after autologous stem cell transplant: results in the novel agent era
Sanjal H Desai, Michael A Spinner, Andrew M Evens, Alice Sykorova, Veronika Bachanova, Gaurav Goyal, Brad Kahl, Kathleen Dorritie, Jacues Azzi, Vaishalee P Kenkre, Cheryl Chang, Jozef Michalka, Stephen M Ansell, Brendon Fusco, Nuttavut Sumransub, Haris Hatic, Raya Saba, Uroosa Ibrahim, Elyse I Harri · 2023
Read Overall survival of patients with cHL who progress after autologous stem cell transplant: results in the novel agent era by Sanjal H Desai, Michael A Spinner, Andrew M Evens, Alice Sykorova, Veronika Bachanova, Gaurav Goyal, Brad Kahl, Kathleen Dorritie, Jacues Azzi, Vaishalee P Kenkre, Cheryl Chang, Jozef Michalka, Stephen M Ansell, Brendon Fusco, Nuttavut Sumransub, Haris Hatic, Raya Saba, Uroosa Ibrahim, Elyse I Harri (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10711178.txt.
Description
Sanjal Desai and co-authors measured how long patients live after Hodgkin lymphoma returns following a stem cell transplant, in a 2023 study. In the past, such patients lived a median of two to three years after relapse. Since then, two drug types, checkpoint inhibitors and a targeted antibody drug, have deepened and lengthened responses. The team gathered records from fifteen centers to update the outlook in this new era.
Of nearly twelve hundred transplant patients, three hundred sixty-seven saw their cancer progress. Their median survival after relapse reached about nine and a half years, far beyond the old figure. Older age, fast relapse, and a hot scan before transplant marked worse odds. Patients whose first salvage used a checkpoint inhibitor lived longer than those who got neither new drug. A second, donor transplant did not add survival in this group.
Catalog record
| CREATOR | Sanjal H Desai, Michael A Spinner, Andrew M Evens, Alice Sykorova, Veronika Bachanova, Gaurav Goyal, Brad Kahl, Kathleen Dorritie, Jacues Azzi, Vaishalee P Kenkre, Cheryl Chang, Jozef Michalka, Stephen M Ansell, Brendon Fusco, Nuttavut Sumransub, Haris Hatic, Raya Saba, Uroosa Ibrahim, Elyse I Harri |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |