Gold Nanocage-Based Multifunctional Nanosensitizers for Programmed Photothermal /Radiation/Chemical Coordinated Therapy Guided by FL/MR/PA Multimodal Imaging

Xinni Pan, Yi Lu, Shanshan Fan, Hao Tang, Haisong Tan, Cheng Cao, Yingsheng Cheng, Yanlei Liu · 2023

Read Gold Nanocage-Based Multifunctional Nanosensitizers for Programmed Photothermal /Radiation/Chemical Coordinated Therapy Guided by FL/MR/PA Multimodal Imaging by Xinni Pan, Yi Lu, Shanshan Fan, Hao Tang, Haisong Tan, Cheng Cao, Yingsheng Cheng, Yanlei Liu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10710274.txt.

Description

Xinni Pan and seven colleagues built gold nanocage particles that combine cancer imaging with three coordinated treatments. Radiotherapy is a mainstay against tumors, but resistant cells and collateral damage limit it. Their particles add manganese dioxide to gold cages, enabling three imaging modes: fluorescence, magnetic resonance, and photoacoustic. The therapy runs in a programmed sequence. Heat treatment comes first, ablating bulky tumor and sensitizing tissue to radiation.

Radiation then shrinks the tumor further, and chemotherapy finishes off small residues and spread. Gold cages convert light to heat efficiently and amplify radiation effects. The twenty twenty-three study presents the design and its rationale as a theranostic platform. Staging the three attacks in order aims to make each one land harder than it would alone.

Catalog record

CREATORXinni Pan, Yi Lu, Shanshan Fan, Hao Tang, Haisong Tan, Cheng Cao, Yingsheng Cheng, Yanlei Liu
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10710274

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