Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study

Irene Santos-Pardo, Nils Witt, Oskar Angerås, Thomas Nyström · 2023

Read Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study by Irene Santos-Pardo, Nils Witt, Oskar Angerås, Thomas Nyström (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10709975.txt.

Description

Santos-Pardo and co-authors present a 2023 trial on whether a diabetes drug helps heart stents heal. People with type 2 diabetes face higher odds of stent clogging and clots. The drug exenatide, a gut-hormone mimic, may calm vessel walls. Thirty-eight patients getting a modern drug-coated stent joined the Rebuild study, half adding weekly exenatide to standard care.

After twelve weeks, a new vessel scan measured how much of each stent strut had grown a cell cover. Coverage was high in both groups, near ninety-five and ninety-one percent. The gap was not significant, and new tissue thickness matched as well. The drug showed no clear healing edge in this small trial.

Catalog record

CREATORIrene Santos-Pardo, Nils Witt, Oskar Angerås, Thomas Nyström
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10709975

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