Leveraging a disulfidptosis‑related lncRNAs signature for predicting the prognosis and immunotherapy of glioma
Di Chen, Qiaoqiao Li, Yuan Xu, Yanfei Wei, Jianguo Li, Xuqiang Zhu, Hongjiang Li, Yan Lu, Xianzhi Liu, Dongming Yan · 2023
Read Leveraging a disulfidptosis‑related lncRNAs signature for predicting the prognosis and immunotherapy of glioma by Di Chen, Qiaoqiao Li, Yuan Xu, Yanfei Wei, Jianguo Li, Xuqiang Zhu, Hongjiang Li, Yan Lu, Xianzhi Liu, Dongming Yan (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10709922.txt.
Description
Di Chen and co-authors built a gene based score to predict outcomes for glioma, a brain tumor with poor survival, in work published in 2023. The score uses long non coding RNAs tied to a newly described form of cell death. Public tumor data were used to build and test the model.
Six such RNAs formed a signature that split patients into high and low risk groups with clearly different survival. The score held up as an independent predictor across checks. Low risk tumors showed quieter immune signals, and drug response data hinted at options that differ by risk group. Lab tests confirmed the RNA levels. The authors offer the signature as a guide for prognosis and therapy choice.
Catalog record
| CREATOR | Di Chen, Qiaoqiao Li, Yuan Xu, Yanfei Wei, Jianguo Li, Xuqiang Zhu, Hongjiang Li, Yan Lu, Xianzhi Liu, Dongming Yan |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |