Hemostatic potential of recombinant von Willebrand factor and standard or pegylated extended half-life recombinant factor VIII on thrombus formation under high shear flow
Hiroaki Yaoi, Yasuaki Shida, Kenichi Ogiwara, Keiji Nogami · 2023
Read Hemostatic potential of recombinant von Willebrand factor and standard or pegylated extended half-life recombinant factor VIII on thrombus formation under high shear flow by Hiroaki Yaoi, Yasuaki Shida, Kenichi Ogiwara, Keiji Nogami (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10709842.txt.
Description
Hiroaki Yaoi and co-authors test how recombinant von Willebrand factor and factor VIII shape clot growth when blood flows fast. Their 2023 study used whole blood from a patient with type one von Willebrand disease.
In tests with a flow chamber, recombinant factor VIII on its own did not lift clot growth. Recombinant von Willebrand factor raised both the share of the surface that was clothed in clot and the height of the clot. The two recombinant goods used as a pair did as well as a good drawn from plasma, at raising the drive to form clots. Like tests used a device made for use in clinics. The results help show how these goods aid hemostasis when blood flows fast. That state is key for care of bleeding.
Catalog record
| CREATOR | Hiroaki Yaoi, Yasuaki Shida, Kenichi Ogiwara, Keiji Nogami |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |