Ag nanorod@PEI-Ag nanohybrid as an excellent signal label for sensitive and rapid detection of serum HER2
Fatemeh Hakimian, Mohammad Mazloum-Ardakani · 2023
Read Ag nanorod@PEI-Ag nanohybrid as an excellent signal label for sensitive and rapid detection of serum HER2 by Fatemeh Hakimian, Mohammad Mazloum-Ardakani (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10709618.txt.
Description
Fatemeh Hakimian and Mohammad Mazloum-Ardakani build, in a 2023 paper, a fast sensor for HER2, a protein that marks an aggressive form of breast cancer. Finding HER2 in blood helps doctors pick the right treatment early. Their sensor uses a new label made of silver nanorods wrapped in a charged polymer dotted with silver. The label both carries a strong electric signal and offers a large sticky surface.
A strand that binds HER2 sits on a gold electrode and catches the protein from a sample. The charged label then clings to the caught protein, and the current from a silver reaction reads out the amount. The sensor responds across a wide range of amounts, spots very tiny traces, and finishes in about half an hour. Tests in human serum show it could suit quick clinical screening.
Catalog record
| CREATOR | Fatemeh Hakimian, Mohammad Mazloum-Ardakani |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |