Genomic surveillance of SARS-CoV-2 reveals highest severity and mortality of delta over other variants: evidence from Cameroon
Joseph Fokam, Rene Ghislain Essomba, Richard Njouom, Marie-Claire A Okomo, Sara Eyangoh, Celestin Godwe, Bryan Tegomoh, John O Otshudiema, Julius Nwobegahay, Lucy Ndip, Blaise Akenji, Desire Takou, Mohamed M M Moctar, Cleophas Kahtita Mbah, Valantine Ngum Ndze, Martin Maidadi-Foudi, Charles Kouanfac · 2023
Read Genomic surveillance of SARS-CoV-2 reveals highest severity and mortality of delta over other variants: evidence from Cameroon by Joseph Fokam, Rene Ghislain Essomba, Richard Njouom, Marie-Claire A Okomo, Sara Eyangoh, Celestin Godwe, Bryan Tegomoh, John O Otshudiema, Julius Nwobegahay, Lucy Ndip, Blaise Akenji, Desire Takou, Mohamed M M Moctar, Cleophas Kahtita Mbah, Valantine Ngum Ndze, Martin Maidadi-Foudi, Charles Kouanfac (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10709425.txt.
Description
Joseph Fokam and co-authors track COVID-19 variants across Cameroon in a 2023 paper. Data from sub-Saharan Africa were scarce during the pandemic, so the national lab network sequenced virus genomes from March 2020 to March 2022. The team matched the lineages to the country's four waves and to how sick patients became.
Of the successful genomes, most belonged to the original lineages, with Delta the largest variant share, then Omicron, Alpha, and Beta. Each wave had its driver: original lineages first, Alpha and Beta next, Delta third, and Omicron last. Death rates per case fell across the waves. Even so, Delta stood out for severity, and the original lineages also drove serious illness. The authors say spread alone did not explain which lineages hurt most.
Catalog record
| CREATOR | Joseph Fokam, Rene Ghislain Essomba, Richard Njouom, Marie-Claire A Okomo, Sara Eyangoh, Celestin Godwe, Bryan Tegomoh, John O Otshudiema, Julius Nwobegahay, Lucy Ndip, Blaise Akenji, Desire Takou, Mohamed M M Moctar, Cleophas Kahtita Mbah, Valantine Ngum Ndze, Martin Maidadi-Foudi, Charles Kouanfac |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |