Biotinylated Quinone as a Chemiluminescence Sensor for Biotin-Avidin Interaction and Biotin Detection Application

Fatema Kaladari, Mahmoud El-Maghrabey, Megumi Kawazato, Naoya Kishikawa, Naotaka Kuroda, Eduard Llobet · 2023

Read Biotinylated Quinone as a Chemiluminescence Sensor for Biotin-Avidin Interaction and Biotin Detection Application by Fatema Kaladari, Mahmoud El-Maghrabey, Megumi Kawazato, Naoya Kishikawa, Naotaka Kuroda, Eduard Llobet (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10708767.txt.

Description

Fatema Kaladari and co-authors build a glowing sensor for vitamin B7. Their 2023 paper deals with biotin, a vitamin mammals must take in, so supplement levels need checking. Stock assays crawl and cost. Their compound ties biotin to a quinone that glows through a redox cycle with a helper and luminol. When avidin, biotin's partner protein, grabs the compound, the glow dims.

Free biotin then fights for the seat and frees the compound, and the glow returns. That contest forms the assay, which read vitamin tablets with sound recovery and tight spread. A no-biotin quinone proved the contest real.

Catalog record

CREATORFatema Kaladari, Mahmoud El-Maghrabey, Megumi Kawazato, Naoya Kishikawa, Naotaka Kuroda, Eduard Llobet
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10708767

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