A Facile and General Oxidative Hydroxylation of Organoboron Compounds: Citric Acid as an Efficient Catalyst in Water to Access Phenolic and Alcoholic Motifs
Jia-Hui Zhou, Xia Chen, Dan Yang, Chun-Yan Liu, Xiao-Yu Zhou, Leonarda Liotta, Valeria La Parola · 2023
Read A Facile and General Oxidative Hydroxylation of Organoboron Compounds: Citric Acid as an Efficient Catalyst in Water to Access Phenolic and Alcoholic Motifs by Jia-Hui Zhou, Xia Chen, Dan Yang, Chun-Yan Liu, Xiao-Yu Zhou, Leonarda Liotta, Valeria La Parola (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10708500.txt.
Description
Turning boron compounds into phenols and alcohols is a staple move in chemical synthesis, usually needing pricey or harsh catalysts. Jia-Hui Zhou and co-authors show citric acid, the sour bite in lemons, can drive the reaction in plain water at room temperature. Hydrogen peroxide supplies the oxygen, and yields reached up to ninety-nine percent across a range of starting materials.
Delicate groups that chemists prize, halogens, nitriles, and nitro groups, survived the bath untouched. Two other boron forms common in laboratories also converted well. The authors present the recipe as a facile, general, and greener route to building blocks found across medicines and materials. Water as solvent and a food-grade catalyst keep the method cheap and benign.
Catalog record
| CREATOR | Jia-Hui Zhou, Xia Chen, Dan Yang, Chun-Yan Liu, Xiao-Yu Zhou, Leonarda Liotta, Valeria La Parola |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |