Helium Cold Atmospheric Plasma Causes Morphological and Biochemical Alterations in Candida albicans Cells
Sabrina de Moura Rovetta-Nogueira, Aline Chiodi Borges, Maurício de Oliveira Filho, Thalita Mayumi Castaldelli Nishime, Luis Rogerio de Oliveira Hein, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito · 2023
Read Helium Cold Atmospheric Plasma Causes Morphological and Biochemical Alterations in Candida albicans Cells by Sabrina de Moura Rovetta-Nogueira, Aline Chiodi Borges, Maurício de Oliveira Filho, Thalita Mayumi Castaldelli Nishime, Luis Rogerio de Oliveira Hein, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10707892.txt.
Description
Sabrina de Moura Rovetta-Nogueira and six co-authors study how cold plasma harms a common yeast fungus, in a 2023 lab study. The fungus, Candida albicans, causes thrush and deeper infections, and cold atmospheric plasma had already been shown to slow it. What the plasma does to the fungal wall was unclear. The team zapped cells with helium plasma, then read shape and chemistry with a fine probe microscope and infrared light.
Treated cells grew rougher and changed shape, much like cells dosed with a known wall drug. Their wall sugars shifted too: one class fell while the building blocks of chitin rose. The authors say the plasma attacks the wall's sugar frame, not just the cell surface. That insight could guide plasma doses for antifungal use. It also hints at pairing plasma with wall-target drugs.
Catalog record
| CREATOR | Sabrina de Moura Rovetta-Nogueira, Aline Chiodi Borges, Maurício de Oliveira Filho, Thalita Mayumi Castaldelli Nishime, Luis Rogerio de Oliveira Hein, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |