Information maximization-based clustering of histopathology images using deep learning

Mahfujul Islam Rumman, Naoaki Ono, Kenoki Ohuchida, MD. Altaf-Ul-Amin, Ming Huang, Shigehiko Kanaya · 2023

Read Information maximization-based clustering of histopathology images using deep learning by Mahfujul Islam Rumman, Naoaki Ono, Kenoki Ohuchida, MD. Altaf-Ul-Amin, Ming Huang, Shigehiko Kanaya (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10707605.txt.

Description

Mahfujul Islam Rumman and co-authors cluster pancreas tissue images without any labels in a 2023 study. Pancreatic cancer hides deep and tangles with vessels, so microscope diagnosis carries heavy weight. Mouse tumors that mimic the human disease supplied whole-slide images.

Random patches from the slides were squeezed by an autoencoder into a compact code space. An information-maximizing method then grouped look-alike patches with no annotation at all. The clusters separate tissue patterns that pathologists care about. Unsupervised sorting could pre-screen slides and flag the odd ones for expert eyes, the authors suggest.

Catalog record

CREATORMahfujul Islam Rumman, Naoaki Ono, Kenoki Ohuchida, MD. Altaf-Ul-Amin, Ming Huang, Shigehiko Kanaya
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10707605

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