Skin Barrier Function: The Interplay of Physical, Chemical, and Immunologic Properties

Paola Baker, Christina Huang, Rakan Radi, Samara B Moll, Emmanuela Jules, Jack L Arbiser, Alexander E Kalyuzhny · 2023

Read Skin Barrier Function: The Interplay of Physical, Chemical, and Immunologic Properties by Paola Baker, Christina Huang, Rakan Radi, Samara B Moll, Emmanuela Jules, Jack L Arbiser, Alexander E Kalyuzhny (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10706187.txt.

Description

Baker and co-authors review in 2023 how the skin barrier works through the interplay of physical, chemical, and immune traits. A sound barrier keeps skin healthy, and its control runs through many molecular and immune signals. The review covers the acid layer on the skin surface, key fats that seal the barrier, and signals such as interleukins and a master inflammation switch.

Understanding healthy control helps doctors design fixes for a broken barrier. Knowing which breaks tie to which diseases, such as eczema like dermatitis or psoriasis, points to new compounds aimed at set pathways. Current and emerging treatments for barrier conditions close the review. Readers get a compact map of skin defense and its failure modes.

Catalog record

CREATORPaola Baker, Christina Huang, Rakan Radi, Samara B Moll, Emmanuela Jules, Jack L Arbiser, Alexander E Kalyuzhny
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10706187

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