Contemporaneous Perioperative Inflammatory and Angiogenic Cytokine Profiles of Surgical Breast, Colorectal, and Prostate Cancer Patients: Clinical Implications

Leili Baghaie, Fiona Haxho, Fleur Leroy, Beth Lewis, Alexander Wawer, Shamano Minhas, William W Harless, Myron R Szewczuk, Li Yang · 2023

Read Contemporaneous Perioperative Inflammatory and Angiogenic Cytokine Profiles of Surgical Breast, Colorectal, and Prostate Cancer Patients: Clinical Implications by Leili Baghaie, Fiona Haxho, Fleur Leroy, Beth Lewis, Alexander Wawer, Shamano Minhas, William W Harless, Myron R Szewczuk, Li Yang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10706122.txt.

Description

Leili Baghaie and co-authors report a clinical study, published in 2023, on the surge of signaling molecules that surgery itself triggers in cancer patients. Surgeons have long suspected that wound healing chemistry can wake leftover cancer cells and speed their spread. The team drew blood from sixty-eight patients with breast, colorectal, or prostate cancer around their operations, at eight time points each.

Protein panels measured dozens of cytokines, chemokines, and growth factors at once. Right after surgery, several pro growth and pro vessel molecules spiked sharply, while other calming factors dropped. The pattern was measured in patients who had no other treatment near the operation, isolating surgery's own fingerprint. The authors argue this window deserves attention in planning care after cancer surgery.

Catalog record

CREATORLeili Baghaie, Fiona Haxho, Fleur Leroy, Beth Lewis, Alexander Wawer, Shamano Minhas, William W Harless, Myron R Szewczuk, Li Yang
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE67 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10706122

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