A Label-Free Aptasensor for Turn-On Fluorescent Detection of Aflatoxin B1 Based on an Aggregation-Induced-Emission-Active Probe and Single-Walled Carbon Nanohorns

Huanhuan Yang, Lei Lv, Mengyu Niu, Dongjie Zhang, Zhijun Guo, Lubomir Lapcik · 2023

Read A Label-Free Aptasensor for Turn-On Fluorescent Detection of Aflatoxin B1 Based on an Aggregation-Induced-Emission-Active Probe and Single-Walled Carbon Nanohorns by Huanhuan Yang, Lei Lv, Mengyu Niu, Dongjie Zhang, Zhijun Guo, Lubomir Lapcik (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10705928.txt.

Description

Huanhuan Yang and co-authors build a glowing sensor for a food toxin in a 2023 paper. Aflatoxin B1 is a poison made by molds that can contaminate food, and checking for it guards public health. Their sensor uses a short DNA strand that folds when it meets the toxin, plus a dye that glows when its molecules clump.

A carbon material in the mix normally dims the dye. When the toxin is present, the folded DNA sticks to the carbon and shields the dye, so the glow survives and its strength reveals how much toxin is there. The test runs in two hours, spots very low levels, ignores other mold toxins, and worked in soy sauce samples with accurate recovery.

Catalog record

CREATORHuanhuan Yang, Lei Lv, Mengyu Niu, Dongjie Zhang, Zhijun Guo, Lubomir Lapcik
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10705928

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